Nov 2, 2021 · p57 is a cyclin dependent kinase inhibitor protein, the product of the paternally imprinted, maternally expressed gene CDKN1C (p57KIP2) located on chromosome 11p15

Cyclin-dependent kinase inhibitor 1C (p57, Kip2), also known as CDKN1C, is a protein which in humans is encoded by the CDKN1C imprinted gene. [5] Cyclin-dependent kinase inhibitor 1C …

Dec 6, 2025 · p57 (Kip 2, CDKN 1C) is an inhibitor of several G1 cyclin complexes and is a negative regulator of cell proliferation.

p57 is a cyclin-dependent kinase (CDK) inhibitor, the first cell cycle regulator that is regulated by imprinting. p57 was initially considered to be a tumor suppressor based on its ability to …

The p57 protein functions as a cyclin-dependent kinase inhibitor, often abbreviated as CDKI. It binds to and deactivates specific enzymes called cyclin-dependent kinases (CDKs), which are …

Jan 1, 2018 · p57 is important during embryonal development and is found in derivatives of all three germ layers. p57 is important also for the differentiation of some adult tissues where it …

Mar 21, 2025 · Let’s break down how p57 aids in the diagnosis of molar pregnancies, the histologic features of complete and partial moles, and how to interpret this marker in routine …

Jun 24, 2014 · Human p57, also designated Cyclin-dependent kinase inhibitor 1C or Kip2, is a 316-amino acid nuclear protein involved in regulation of cell proliferation. p57 is an inhibitor of …

p57 or p57KIP2 is a tumor suppressor human gene on chromosome 11 (11p15) and belongs to the cip/kip gene family. It encodes a cell cycle inhibitor that binds to G1 cyclin-CDK …

Here we described a series of cases of p57-negative PHMs and nonmolar abortus specimens with emphasis on the etiology, genetics, and clinical significance.