These factors then induce myostatin-specific gene regulation. When applied to myoblasts, myostatin inhibits their proliferation and either initiates differentiation or stimulates quiescence.

Jun 23, 2022 · Myostatin (MSTN) is a well-reported negative regulator of muscle growth and a member of the transforming growth factor (TGF) family. MSTN has important functions in skeletal muscle …

Myostatin - an overview | ScienceDirect Topics

Jun 14, 2025 · Myostatin, also called GDF-8 (growth differentiation factor 8), is a protein secreted primarily in skeletal muscle cells. It belongs to the TGF-β (transforming growth factor-beta) family—a …

Sep 29, 2025 · Myostatin is a protein that acts as a brake on muscle development. Scientists call it growth differentiation factor 8. It belongs to the transforming growth factor beta family. In simple …

Myostatin is found almost exclusively in muscles used for movement (skeletal muscles), where it is active both before and after birth. This protein normally limits muscle growth, ensuring that muscles …

Jul 25, 2025 · Myostatin is a protein, specifically a type of signaling molecule known as a myokine, primarily produced by muscle cells. It functions as a negative regulator, meaning it acts to limit or …

Aug 14, 2025 · Myostatin (MSTN), a pivotal regulator of skeletal muscle homeostasis, belongs to the TGF-β family and functions as a potent inhibitor of muscle hypertrophy.

Dec 15, 2022 · Myostatin is a human growth factor that prevents excessive muscle growth, and abnormally high levels can cause the loss of muscle mass. Despite the lack of proper data, myostatin …

Dec 24, 2021 · Myostatin, also known as growth differentiation factor-8 (GDF-8), is a member of the TGF-β superfamily and negatively regulates the growth and development of skeletal muscle through …