Extracellular vesicles (EVs) are tiny biological bubbles that carry nucleic acids and proteins between cells, playing an essential role in tissue repair, neuroprotection and immune health. By ...

Stanford Medicine researchers have developed an experimental nasal vaccine that shielded mouse lungs for at least three months against a striking range of respiratory threats, from SARS-CoV-2 and ...

Mycobacterium tuberculosis, the pathogen responsible for tuberculosis, has evolved a remarkably layered set of molecular ...

In an early animal test, a new nasal-spray vaccine has shown promise against a variety of germs and a common allergen, ...

Carfilzomib prevented BCMA degradation, increased target density, and improved CAR T susceptibility by ~26%–28% in vitro, while enhancing xenograft antitumor activity without worsening T-cell ...

In a syngeneic CT26 model, murine STC-1010 significantly inhibits tumor growth and extends survival by 40%. New mechanistic datas reveal expansion of CD4 and CD8 T cells in draining lymph nodes ...

Scientists discovered that rearranging a peptide’s placement in a spherical nucleic acid vaccine dramatically improves immune response against HPV-driven tumors. The findings have the potential to ...

Northwestern researchers have shown that when it comes to cancer vaccines, arrangement can be just as important as ingredients. By repositioning a small fragment of an HPV protein on a DNA-based ...

In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite ...

A structurally tuned HPV cancer SNA vaccine boosts CD8⁺ T‑cell responses and slows tumor growth in mice and patient‑derived spheroids, a study shows.

A new vaccine design uses folded DNA to steer the immune system toward producing the rare immune cells needed to make protective antibodies against HIV.