Contemporary Pediatrics

FDA approves gadopiclenol extension in neonates

The gadopiclenol extension for use in infants and neonates offers high-quality MRI contrast enhancement at half the standard gadolinium dose. The FDA has approved an extension of intravenous ...
Contemporary Pediatrics

Study finds prenatal exposure to dozens more PFAS than previously detected in cord blood

Nontargeted testing identified 42 PFAS in cord blood, far exceeding the 8 compounds measured by traditional targeted methods, suggesting broader prenatal exposure. Cumulative exposure estimates ...
contemporarypediatrics

FDA approves ferric maltol for iron deficiency in children 10 years and older

New pediatric indication: Ferric maltol (ACCRUFeR) is now FDA approved for iron deficiency in children aged 10 years and older, expanding beyond its 2019 adult indication. Clinical efficacy: In the ...
contemporarypediatrics

Jeanette Stingone, PhD, highlights the importance of early intervention for academic outcomes

New research demonstrates that targeted early intervention services improve academic performance and long-term health for children with developmental disabilities. In a Contemporary Pediatrics® ...
contemporarypediatrics

Kenneth J. Moise Jr, MD, discusses potential of FcRn blockade to reduce invasive treatment in HDFN

Phase 2 data suggest FcRn blockade may reduce maternal IgG and placental antibody transfer in HDFN without excess infant infections. Hemolytic disease of the fetus and newborn (HDFN) remains a serious ...
contemporarypediatrics

Breztri Aerosphere shows positive phase 3 data against uncontrolled asthma

In the phase 3 KALOS and LOGOS trials, single-inhaler fixed-dose triple therapy Breztri Aerosphere significantly improved lung function and reduced severe exacerbation rates vs dual-combination ...
contemporarypediatrics

Oral infigratinib linked to improved growth and proportionality in achondroplasia

In the PROPEL 3 trial, oral infigratinib demonstrated superior annualized height velocity vs placebo, with an LS mean treatment difference of 1.74 cm per year. The therapy showed significant gains in ...
contemporarypediatrics

Special Report: Dietary Guidelines miss key pediatric guidance

Experts flag missing pediatric guidance in the 2025–2030 Dietary Guidelines, including infant safety, iron intake, and early nutrition education. In episode 5 of this Special Report, Colleen Sloan, PA ...
contemporarypediatrics

Special Report: Dietary Guidelines miss key nutrition issues

Experts highlight gaps in the new Dietary Guidelines, including fiber, whole grains, plant-based milks, and simplified alcohol guidance. In episode 4 of this Special Report, Colleen Sloan, PA-C, RDN, ...
contemporarypediatrics

AbbVie submits FDA, EMA applications for upadacitinib (RINVOQ) in non-segmental vitiligo for 12 years and older

AbbVie submitted FDA and EMA applications seeking approval of upadacitinib (RINVOQ) 15 mg once daily for adults and adolescents aged 12 years and older with non-segmental vitiligo. Phase 3 Viti-Up ...
contemporarypediatrics

FDA issues complete response letter for sublingual epinephrine film Anaphylm

CRL focused on usability, not efficacy or manufacturing: The FDA’s Complete Response Letter for Anaphylm cited deficiencies limited to human factors, labeling, and a single supportive PK study; no CMC ...