Oxidative stress is caused by an imbalance between production and accumulation of oxygen reactive species (ROS) in cells and tissues. Manganese superoxide dismutase (MnSOD) is an antioxidant enzyme ...

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

A new study published in Nature Structural & Molecular Biology reveals how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that ...

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system. Enzymes usually clear these nucleic acids before they cause an issue, but when these ...

In a discovery three decades in the making, scientists at Rutgers and Brookhaven National Laboratory have acquired detailed knowledge about the internal structures and mode of regulation for a ...