Recent research indicates that the nature of activity has a substantial effect on both atherogenesis and vascular remodeling. For example, resistance training may affect coronary compliance and plaque ...
BACKGROUND: The entrance of naive T cells into lymph nodes (LNs) is a crucial step for induction of heart transplant acceptance under costimulatory blockade. Specialized blood vessels within the LN ...
Risk prediction has been used in the primary prevention of cardiovascular disease for >3 decades. Contemporary cardiovascular risk assessment relies on multivariable models, which integrate ...
BACKGROUND: We aimed to examine how coronary artery calcium (CAC) and its progression relate to cognitive function in midlife, an important time for cognitive aging. METHODS: We studied participants ...
BACKGROUND: It remains unclear whether social determinants contribute to major ECG abnormalities (MEA), an early marker of cardiovascular disease, which predicts adverse cardiovascular events and ...
Clonal hematopoiesis (CH), the benign clonal expansion of hematopoietic stem cells, is often caused by somatic sequence variations in genes associated with hematologic malignancies. Over the past ...
BACKGROUND: Hypertensive disorders of pregnancy (HDP) are associated with increased long-term risk of both maternal and offspring cardiovascular disease. The incidence of HDP has increased ...
Targeted, digital recruitment strategies such as tailored websites using motivational themes may improve recruitment in clinical trials, but their effectiveness remains unclear. We hypothesized that ...
Studies that include a large number of VTE cases diagnosed by autopsy generally report a higher proportion of cases with PE than DVT. The yearly incidence of PE and DVT was 205 and 182 per 100,000, ...
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 nuclease (Cas9)-based transcriptional repressors (CRISPRi) have emerged as powerful tools for functional ...
Cardiac troponin (cTn) testing is an essential component of the diagnostic workup and management of acute coronary syndromes (ACS). Although over the past 15 years the diagnostic performance of the ...
BACKGROUND: Mental stress-induced myocardial ischemia is often clinically silent and associated with increased cardiovascular risk, particularly in women. Conventional ECG-based detection is limited, ...