When suspended fibroblasts encounter a substratum such as fibronectin, they spread and then generate stable sites of cell–substratum contact, or focal adhesions (FAs). The FA protein talin links actin ...

Physical forces from gravity, muscle contraction, and more have strong impacts on how the cells in our bodies behave. For ...

Focal adhesion turnover is essential for cell migration. New results show that the talin head liberated from talin by calpain II cleavage has a key role in these events, and that its levels are ...

A team of researchers at Åbo Akademi University in Finland made a surprising discovery. They found that Talin-1, a protein primarily known for its role in cell adhesion at the periphery of the cell, ...

Talin is a protein that controls cellular attachment and movement, but its malfunctioning also allows cancer cells to spread. DCL1 is a tumor-suppressing protein. But scientists don’t fully understand ...