Acid, bile, pancreatic juice, and IgA in the gut lumen, the tight junctions between intestinal epithelial cells, and immune cells in the lamina propria normally work in conjunction to prevent the ...

NASH is a potentially progressive type of nonalcoholic fatty liver disease (NAFLD). Panels A and B show characteristic histologic features of NASH in liver-biopsy specimens: ballooned hepatocytes ...

The pathogenic role of precipitating factors, well-recognized in the encephalopathy of cirrhosis, is often overlooked in ALF. Patients with acute liver failure may develop encephalopathy from the use ...

As a result of advances in sanitation and medical care, populations in the developed world are reaching dramatically higher ages. In aging populations, there is an increase in liver disease, which is ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated ...

Cirrhosis is a chronic and progressive liver disease that occurs when scar tissue gradually replaces healthy liver tissue. Certain conditions, such as hepatitis B and C, can cause post-necrotic ...

Body composition—the distribution of bone, muscle, and fat in the body—can yield vital information on the metabolic and nutritional status of a patient. Several studies have demonstrated the impact of ...

Decompensated cirrhosis describes the complications of advanced liver disease. People with this condition are nearing end-stage liver failure and may need a liver transplant. People with compensated ...

Hepatic encephalopathy (HE) in acute liver injury signifies a serious prognosis. Brain edema and intracranial hypertension are major causes of death in this syndrome. Comparison of HE in acute liver ...