Addiction has causes that are neurobiological, psychological and structural. Treating these drivers is as important as managing the initial withdrawal. Medically managed withdrawal does not restore ...

Dopamine—a neurotransmitter responsible for influencing motivation, pleasure, mood and learning in the brain—has experienced ...

Explore the connections between the world of neuroscience and nuances of substance use disorders with our inaugural episode of In Such a Place. We’ll speak with Dr. Anna Radke, a leading expert in the ...

Health Affairs' Rob Lott interviews Nora Volkow, director of the National Institute on Drug Abuse (NIDA) at the National Institutes of Health, to discuss addiction as a brain disorder, treatments for ...

Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and ...

Post-mortem brain analysis shows decades of alcohol use significantly alter endocannabinoid gene expression in the prefrontal cortex and nucleus accumbens. Increased CB1, reduced CB2, altered GPR55 ...

Methamphetamine addiction has a way of looping back on itself. A rush of pleasure pulls you in, cravings follow, and the ...

For years, addiction was seen as a matter of personal failure—a bad habit or a lack of discipline. People believed those who struggled with substance abuse could stop if they simply wanted to. But ...

Mindfulness, holistic care, and neuroscience are reshaping addiction treatment and offering hope for recovery. Mindfulness, holistic care, and neuroscience are reshaping addiction treatment and ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...