Ketamine use disorder is a serious and growing problem of increased non-prescribed ketamine use among young users, ages 16-30. Linda Cottler, Ph.D., and her fellow researchers at the University of ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

D epression can be challenging to treat. Typical antidepressants, which affect levels of chemicals in the brain involved in mood regulation, have been evolving for decades. But recent findings ...

Major depressive disorder (MDD) is a leading cause of disability worldwide, with a significant proportion of patients (10-20%) progressing to treatment-resistant depression (TRD). TRD is defined by a ...

For example, NMDA receptors are involved in the formation of memories but not in the retention of old memories; similarly, patients with schizophrenia have trouble forming, but not retaining, memories ...

Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor (NMDAR)—long studied primarily for its role in learning and memory—also plays a crucial role in stabilizing ...